Chloramphenicol Palmitate
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Small Industries Development Organization
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Abstract
Chloramphenicol is the specific drug
for control and cure of typhoid and
broad-spectrum bacterial diseases.
Chloramphenicol finds extensive use
through tablets and capsules while
chloramphenicol palmitate is used to
formulate syrups. The structural formula
for chloramphenicol-palmitate is
represented as:
H NH COCHCI2
| |
O2N ā C ā Cā CH2 OCO (CH2)14 CH3
| |
OH H
It lacks the bitter taste of
chloramphenicol. It is hydrolysed in the
upper intestinal tract into the parent
drug, however, it does not share the
topical efficiency of the parent drug. Its
toxicity is like that of chloramphenicol.